Enzymatic Sclerostomy
نویسندگان
چکیده
منابع مشابه
Enzymatic sclerostomy: pilot human study.
OBJECTIVE To evaluate the feasibility and safety of enzymatic sclerostomy as a new modality to lower intraocular pressure in patients with open-angle glaucoma. METHODS This single-center, prospective, noncomparative, interventional case series included 15 blind symptomatic eyes of 15 patients with primary open-angle glaucoma. Enzymatic sclerostomy was performed with the patient under topical ...
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A modified open mask system incorporating an en face air jet to dry the target area during ablation and a conjunctival plication mechanism, which allows ab externo delivery of the 193 nm excimer laser without prior conjunctival dissection, has been developed to form small bore sclerostomies accurately and atraumatically. Full thickness sclerostomies, and sclerostomies guarded by a smaller inter...
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Carbohydrate-mediated biochemical recognition processes are potential targets for drug development. The synthesis of complex carbohydrates and related structures, however, has been a difficult task, especially from practical point of view. New solutionand solidphase methods based on enzymatic and a combined enzymatic and chemical procedure have recently been developed for the practical synthesi...
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Rat liver microsomal glycoproteins were purified by affinity chromatography on concanavalin A Sepharose columns from membrane and content fractions, separated from rough microsomes (RM) treated with low concentrations of deoxycholate (DOC). All periodic acid-Schiff (PAS)-positive glycoproteins of RM showed affinity for concanavalin A Sepharose; even after sodium dodecyl sulfate (SDS) acrylamide...
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It has been argued that a substrate-induced conformational change involving the orientation of catalytic groups cannot affect the specificity for two substrates in an enzymatic system where the chemical step is rate limiting, because such an induced fit would alter the catalytic efficiency for both to an equal extent. To the contrary, the generalized induced-fit treatment described here shows t...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2002
ISSN: 0003-9950
DOI: 10.1001/archopht.120.5.548